Abstract:
Objective To investigate the influence factors of skin and mucous membrane depth separation after sigmoid colostomy.
Methods The clinical data of 450 patients receiving combined abdominal and perineal resection for low rectal cancer admitted to the Colorectal Surgery Department of Cancer Hospital, Chinese Academy of Medical Sciences from March 2016 to May 2019 were retrospectively analyzed, univariate analysis and Logistic dichotomy multivariate regression analysis were used to study the clinical independent influencing factors of skin mucous membrane depth separation.
Results Among the 450 patients, 36 (8%) had skin and mucous membrane depth separation. Unifactor analysis showed that preoperative neoadjuvant therapy (P=0.028), diabetes mellitus (P=0.008), hypoalbuminemia (P=0.010), postoperative intestinal mucosal necrosis (P=0.030), infection (P=0.038) were the influencing factors for depth separation of skin and mucosa.The results of multivariate regression analysis showed that hypoalbuminemia(OR=2.514, 95%CI: 1.217~5.134, P=0.01),diabetes mellitus (OR=3.014, 95%CI: 1.287~7.057; P=0.011), intestinal mucosal necrosis (OR=3.155, 95%CI: 1.036~9.610; P=0.043), and fat liquefaction in local tissue (OR=5.467, 95%CI: 1.754~17.038; P=0.003) were independent influencing factors for depth separation of skin and mucosa.
Conclusion Hypoalbuminemia, combined with diabetes mellitus, postoperative intestinal stoma mucosa necrosis and local tissue fat liquefaction were the independent influencing factors for the separation of skin and mucosa after intestinal stoma.
Key words:
Colon, sigmoid,
Colostomy,
Skin mucous membrane depth separation,
Influencing factors
Hong Yun, Yi Zhang, Hongxia Yu, Mengyi Zhang. Exploring influencing factors on sigmoid colostomy depth of skin mucous membrane separation[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2020, 09(01): 92-95.