The China Cancer Registration Annual Report is a summary of China′s cancer registration data and statistical results. It is widely used in the research and prevention of cancer, providing basic reference data for cancer prevention and research in China. Colorectal cancer, as one of the common malignant tumors in China, is receiving more and more attention from the outside world. Especially in the past 20 years, the incidence of colorectal cancer in the developed countries represented by the United States has shown a significant decline, but in China it shows an increasing trend. This growth change is worthy of attention and in-depth analysis. Therefore, the author combined with the data of the annual report to analyze the epidemiological characteristics of colorectal cancer in China. And aiming at the strategies and measures taken in the disease control, explore the new direction of prevention and treatment of colorectal cancer with Chinese characteristics.