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Chinese Journal of Colorectal Diseases(Electronic Edition) ›› 2017, Vol. 06 ›› Issue (03): 234-237. doi: 10.3877/cma.j.issn.2095-3224.2017.03.013

Special Issue:

• Review • Previous Articles     Next Articles

The analysis of efficacy and safety of thalidomide in inflammatory bowel disease

Dan Mu1, Yueyue Li1, Yanqing Li1,()   

  1. 1. Department of Gastroenterology, Laboratory of Translational Gastroenterology, Shandong University, Qilu Hospital, Jinan 250012, China
  • Received:2016-10-19 Online:2017-06-25 Published:2017-06-25
  • Contact: Yanqing Li
  • About author:
    Corresponding author: Li Yanqing, Email:

Abstract:

Thalidomide has received widespread attention as a cheap drug which has properties of anti-inflammatory, immunosuppression and immunomodulatory. This article elaborates the efficacy and safety of thalidomide in inflammatory bowel disease, and finds it possible mechanism. With the deepening of the research, thalidomide can be used as a salvage therapy when inflammatory bowel disease cannot induce and maintain remissions by glucocorticoid, immunosuppressive agents, biologic agents and so on.

Key words: Inflammatory bowel disease, Thalidomide, Effectiveness, Safety

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