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Chinese Journal of Colorectal Diseases(Electronic Edition) ›› 2016, Vol. 05 ›› Issue (02): 127-132. doi: 10.3877/cma.j.issn.2095-3224.2016.02.04

Special Issue:

• Forum for Expert • Previous Articles     Next Articles

Advances in preoperative radiation of locally advanced rectal cancer

Juefeng Wan1, Zhen Zhang1,()   

  1. 1. Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
  • Received:2016-01-02 Online:2016-04-25 Published:2016-04-25
  • Contact: Zhen Zhang
  • About author:
    Corresponding author: Zhang Zhen, Email:

Abstract:

Neoadjuvant chemoradiation combined with radical surgery has been established as the standard care for locally advanced rectal cancer after the randomized phase III clinical trial CAO/ARO/AIO-94 in 2004. This paper reviewed advances in chemotherapy combined with radiation, neoadjuvant chemotherapy before chemoradiaiton, prolonging the interval between chemoradiaiton and surgery, organ preservation after chemoradiaiton and adaptability of Chinese patients which have all contributed to improvements of efficacy of chemoradiaiton and individualized treatment.

Key words: Rectal neoplasms, Therapy, Advances

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