Research of the relationship between Survivin and Caspase-9 expression in colorectal cancer

doi:10.3877/cma.j.issn.2095-3224.2015.06.15

Abstract

Abstract:

Colorectal cancer is one of the most serious threaten disease to human health. It is the result of many factors, the abnormal expression of the genes which regulate apoptosis play an important role in the development of colorectal cancer. Survivin and Caspase-9 are associated with the regulation of apoptosis, their abnormal activation and inactivation are closely related to the occurrence of colorectal cancer. Previous studies have indicated that the relationship between Caspase-9、Survivin and the invasion, differentiation, staging and lymph node metastasis of colorectal cancer remain exist controversy. There are clnical value in both of them in the aspects of diagnosis, prognosis and targeted therapy colorectal cancer.

Key words: Colorectal cancer, Apoptosis, Survivin, Caspase-9

Yan Zhao, Zhiqiang Wang. Research of the relationship between Survivin and Caspase-9 expression in colorectal cancer[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2015, 04(06): 645-647.

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https://zhjzcjbdzzz.cma-cmc.com.cn/EN/Y2015/V04/I06/645

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