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中华结直肠疾病电子杂志 ›› 2024, Vol. 13 ›› Issue (06) : 524 -528. doi: 10.3877/cma.j.issn.2095-3224.2024.06.012

综述

中性粒细胞胞外诱捕网在结直肠癌中的研究进展
赵泽云1, 李建男1, 王旻1,()   
  1. 1.130022 长春,吉林大学第二医院结直肠肛门外科
  • 收稿日期:2024-07-31 出版日期:2024-12-25
  • 通信作者: 王旻
  • 基金资助:
    吉林省科技厅项目(No.20230203056SF,No.YDZJ202201ZYTS004)

Research progress of neutrophil extracellular traps in colorectal cancer

Zeyun Zhao1, Jiannan Li1, Min Wang1,()   

  1. 1.Department of Colorectal and Anal Surgery, the Second Hospital of Jilin University, Changchun 130022,China
  • Received:2024-07-31 Published:2024-12-25
  • Corresponding author: Min Wang
引用本文:

赵泽云, 李建男, 王旻. 中性粒细胞胞外诱捕网在结直肠癌中的研究进展[J/OL]. 中华结直肠疾病电子杂志, 2024, 13(06): 524-528.

Zeyun Zhao, Jiannan Li, Min Wang. Research progress of neutrophil extracellular traps in colorectal cancer[J/OL]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2024, 13(06): 524-528.

中性粒细胞胞外诱捕网(NETs)是由中性粒细胞产生的一种网状结构。越来越多证据表明其与多种癌症的进展、侵袭、迁移等有着密切的联系。目前,结直肠癌的发病机制尚不清楚,既往对NETs 在结直肠中的作用也无系统综述。本文全面阐述了NETs 的生物学特征及其与癌症之间复杂的关系,特别聚焦于NETs 在结直肠癌中的作用机制,旨在为探索结直肠癌的发病机制及开发新型治疗策略提供新的视角与思路。

Neutrophil extracellular traps (NETs) is a kind of reticular structure produced by neutrophils.More and more evidence suggests that it is closely associated with the progression, invasion,and migration of various cancers.Currently, the pathogenesis of colorectal cancer is unclear, and there is no previous systematic review of the role of NETs in the colorectum.This article comprehensively describes the biological characteristics of NETs and their intricate relationship with cancer, with a special focus on the specific mechanism of NETs in colorectal cancer, aiming to provide new perspectives and ideas for exploring the pathogenesis and developing novel therapeutic strategies for colorectal cancer.

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