切换至 "中华医学电子期刊资源库"

中华结直肠疾病电子杂志 ›› 2015, Vol. 04 ›› Issue (06) : 653 -655. doi: 10.3877/cma.j.issn.2095-3224.2015.06.17

所属专题: 文献

经验交流

腹腔镜下结直肠癌肝转移一期切除的临床研究
王勇1, 胡俊1, 张冬生1, 封益飞1, 傅赞1, 孙跃明1,()   
  1. 1. 210000 南京医科大学第一附属医院结直肠外科
  • 收稿日期:2015-11-12 出版日期:2015-12-25
  • 通信作者: 孙跃明
  • 基金资助:
    教育部基金项目(2012YQ030261); 江苏省科技厅基础研究计划(BK20131448)

Analysis of simultaneous laparoscopic resection for synchronous colorectal carcinoma liver metastasis

Yong Wang1, Jun Hu1, Dongsheng Zhang1, Yifei Feng1, Zan Fu1, Yueming Sun1,()   

  1. 1. Department of colorectal surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China
  • Received:2015-11-12 Published:2015-12-25
  • Corresponding author: Yueming Sun
  • About author:
    Corresponding author: Sun Yueming, Email:
引用本文:

王勇, 胡俊, 张冬生, 封益飞, 傅赞, 孙跃明. 腹腔镜下结直肠癌肝转移一期切除的临床研究[J]. 中华结直肠疾病电子杂志, 2015, 04(06): 653-655.

Yong Wang, Jun Hu, Dongsheng Zhang, Yifei Feng, Zan Fu, Yueming Sun. Analysis of simultaneous laparoscopic resection for synchronous colorectal carcinoma liver metastasis[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2015, 04(06): 653-655.

目的

分析腹腔镜下同时行结直肠癌切除术合并肝转移癌切除术的可行性及安全性。

方法

选取26例江苏省人民医院结直肠外科在2013年8月至2015年5月期间完成一期切除结直肠癌原发灶合并肝转移癌切除术的病历资料,观察一期切除的可行性(术中出血、手术时间和中转开腹率)、安全性(术后并发症)和治疗效果(术后恢复情况)。

结果

26例一期手术过程顺利,都获得成功。其中腔镜下结直肠癌原发灶及肝转移癌同时切除共有16例,腔镜下结直肠癌切除术加开放肝转移癌切除术共有10例。手术时间为(205.12±49.09)min,术中出血量为(296.84±376.53)ml,术后消化道排气时间(2.62±0.56)d,术后住院时间(13.92±6.80)d。术后发生腹腔感染2例,肠瘘1例,自发性气胸1例。余者均恢复良好。

结论

腹腔镜结直肠癌原发灶及肝转移癌的一期切除安全可行,具有较好的疗效。

Objective

To evaluate the security and feasibility analysis of resection for synchronous colorectal carcinoma liver metastasis at the same stage.

Methods

Twenty six colorectal cancer with hepatic metastasis patients were selected between August 2013 and May 2015 at the First Affiliated Hospital of Nanjing Medical University and treated by the simultaneous resected surgery of the primary cancer and hepatic metastasis. At the same time, we investigated the total surgery procedure of feasibility, security and effect of treatment.

Results

The surgical operation procedure of 26 patients were completely successful. There are 16 patients with simultaneous laparoscopic resection of the colorectal cancer and liver metastasis surgery. The other cases were accepted laparoscopic resection the colorectal cancer plus liver metastases resection with open surgery.The mean operation time was (205.12±49.09) min. The mean account of operation bleeding loss was (296.84±376.53) ml. The mean postoperative gastrointestinal function recovery time was (2.62±0.56) d. The mean postoperative hospital stay was (13.92±6.80) d. The postoperative abdominal infection occurred in 2 cases, intestinal fistula in 1 case, 1 case with spontaneous pneumothorax. The rest were recovered well.

Conclusions

First phase of the laparoscopic surgery for colorectal cancer primary tumors and liver metastatic carcinoma resection is safe and feasible, it has a good curative effect and positive prospect.

[1]
刘荫华,姚宏伟.结直肠癌外科手术的原则与进展.中华消化外科杂志, 2013, 12(6): 401-404.
[2]
Van Cutsem E, Rivera F, Berry S, et al.Safety and efficacy of first-line bevacizumab with FOLFOX, XELOX, FOLFIRI and fluoropyrimidines in metastatic colorectal cancer: the BEAT study.Ann Oncol. 2009, 20(11): 1842-1847.
[3]
Stangl R, Altendorf-Hofmann A, Charnley RM, et al. Factors influencing the natural history of colorectal liver metastases. Lancet. 1994, 343(8910): 1405-1410.
[4]
Vignali A, Ghirardelli L, Di Palo S, et al. Laparoscopic treatment of advanced colonic cancer: a case-matched control with open surgery.Colorectal Dis, 2013, 15 (8): 944-948.
[5]
郑树国,李建伟,陈健,等.腹腔镜肝切除术临床应用的经验体会.中华肝胆外科杂志, 2011, 17 (8): 614-617.
[6]
Takahashi M, Wakabayashi G, Nitta H, et al.Pure laparoscopic right hepatectomy by anterior approach with hanging maneuver for large intrahepatic cholangiocarcinoma.Surg Endosc. 2013, 27 (12): 4732-4733.
[7]
Ikeda T, Mano Y, Morita K, et al.Pure laparoscopic hepatectomy in semiprone position for right hepatic major resection.J Hepatobiliary Pancreat Sci, 2013, 20 (2): 145-150.
[8]
Garden OJ, Rees M, Poston GJ, et al. Guidelines for resection of colorectal cancer liver metastases. Gut, 2006, 55 (suppl 3):1-8.
[9]
林俊忠,潘志忠.结直肠癌肝转移外科治疗的争议.中华胃肠外科杂志, 2013, 16 (8): 714-717.
[10]
Weber JC, Bachellier P, Oussoultzoglou E, Jaeck D.Simultaneous resection of colorectal primary tumour and synchronous liver metastases.Br J Surg, 2003, 90 (8): 956-962.
[11]
Martin R, Paty P, Fong Y, et al.Simultaneous liver and colorectal resections are safe for synchronous colorectal liver metastasis. J Am Coll Surg, 2003, 197 (2): 233-241.
[12]
赵明,潘长穿,李旺,黄子林,王键鹏,李宇红,吴沛宏.肝动脉灌注氟尿苷优化结直肠癌肝转移患者的化疗方案的探索性研究.中山大学学报(医学科学版).2011, 32 (3): 348-354.
[13]
周正,杜云峰,宋立伟,等.腹腔镜切除同时性肝转移Ⅳ期大肠癌的临床研究.中华临床医师杂志(电子版).2010, 04 (7): 981-984.
[1] 李凯, 陈淋, 向涵, 苏怀东, 张伟. 一种U型记忆合金线在经脐单孔腹腔镜阑尾切除术中的临床应用[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 15-15.
[2] 杜晓辉, 崔建新. 腹腔镜右半结肠癌D3根治术淋巴结清扫范围与策略[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 5-8.
[3] 周岩冰, 刘晓东. 腹腔镜右半结肠癌D3根治术消化道吻合重建方式的选择[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 9-13.
[4] 唐旭, 韩冰, 刘威, 陈茹星. 结直肠癌根治术后隐匿性肝转移危险因素分析及预测模型构建[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 16-20.
[5] 张生军, 赵阿静, 李守博, 郝祥宏, 刘敏丽. 高糖通过HGF/c-met通路促进结直肠癌侵袭和迁移的实验研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 21-24.
[6] 张焱辉, 张蛟, 朱志贤. 留置肛管在中低位直肠癌新辅助放化疗后腹腔镜TME术中的临床研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 25-28.
[7] 王春荣, 陈姜, 喻晨. 循Glisson蒂鞘外解剖、Laennec膜入路腹腔镜解剖性左半肝切除术临床应用[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 37-40.
[8] 李晓玉, 江庆, 汤海琴, 罗静枝. 围手术期综合管理对胆总管结石并急性胆管炎患者ERCP +LC术后心肌损伤的影响研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 57-60.
[9] 甄子铂, 刘金虎. 基于列线图模型探究静脉全身麻醉腹腔镜胆囊切除术患者术后肠道功能紊乱的影响因素[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 61-65.
[10] 逄世江, 黄艳艳, 朱冠烈. 改良π形吻合在腹腔镜全胃切除消化道重建中的安全性和有效性研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 66-69.
[11] 曹迪, 张玉茹. 经腹腔镜生物补片修补直肠癌根治术后盆底疝1例[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 115-116.
[12] 晏晴艳, 雍晓梅, 罗洪, 杜敏. 成都地区老年转移性乳腺癌的预后及生存因素研究[J]. 中华普外科手术学杂志(电子版), 2023, 17(06): 636-638.
[13] 莫波, 王佩, 王恒, 何志军, 梁俊, 郝志楠. 腹腔镜胃癌根治术与改良胃癌根治术治疗早期胃癌的疗效[J]. 中华普外科手术学杂志(电子版), 2023, 17(06): 644-647.
[14] 叶晋生, 路夷平, 梁燕凯, 于淼, 冀祯, 贺志坚, 张洪海, 王洁. 腹腔镜下应用生物补片修补直肠术后盆底缺损的疗效[J]. 中华疝和腹壁外科杂志(电子版), 2023, 17(06): 688-691.
[15] 夏松, 姚嗣会, 汪勇刚. 经腹腹膜前与疝环充填式疝修补术治疗腹股沟疝的对照研究[J]. 中华疝和腹壁外科杂志(电子版), 2023, 17(06): 702-705.
阅读次数
全文


摘要