结直肠癌是我国的常见恶性肿瘤，发病率居第三位。约20%的结直肠癌初诊时就伴有远处转移，其中肺是最常见的转移部位之一。大量文献表明，对于结直肠癌伴有局限性肺转移的患者手术切除转移病灶，术后的5年生存率为21%～64%。存在其他可切除转移灶并不是手术禁忌。对于手术耐受良好的肺部转移瘤术后复发的患者，再次手术仍可生存获益。距离病灶0.5cm～1.0cm楔形切除是肺外周型病灶的经典术式。对于结直肠癌肺转移瘤手术胸腔淋巴结清扫仍有不同观点。目前公认的结直肠癌肺转移预后不良的因素包括：多发肺转移瘤、癌胚抗原水平升高、胸内淋巴结转移、无瘤间期较短。基于精准医学的个体化治疗将是未来进一步改善预后的关键。

Colorectal cancer is the third most common malignancy in China.About 20% patients have distant metastasis at the time of diagnosis.The lung is one of the most frequently involved organs.Massive documents indicate that for patients with limited lung metastasis, 5 year survival following surgical resection would be 21%-64%, simultaneous resectable other metastatic lesion should not be the contra-indication for surgery.Patients with good tolerance of surgery would still benefit from resection of the recurrent tumor after initial resection of lung metastatic tumor.Wedge resection with resection margin of 0.5cm~1.0cm is the standard of care for peripheral metastatic tumors.There is much controversy on the dissection of the chest lymph nodes.Multiple lung metastatic tumor, elevated CEA level, lymph node metastasis in the chest, and the short tumor free interval are factors indicating poor prognosis.For patients with lung metastasis of colorectal cancer, individualized therapy on the basis of precision medicine is the key point to increase the survival rate in the future.